Overexpressed hPTTG1 promotes breast cancer cell invasion and metastasis by regulating GEF-H1/RhoA signalling

Human pituitary tumour-transforming gene 1 (hPTTG1) is an oncogenic transcription factor that is overexpressed in many tumour types, especially tumours with metastatic abilities. However, how hPTTG1 overexpression drives metastasis is not yet clear. As a transcription factor, hPTTG1 may promote meta...

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Detalles Bibliográficos
Autores principales: Liao, Y C, Ruan, J W, Lua, I, Li, M H, Chen, W L, Wang, J R Y, Kao, R H, Chen, J H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381367/
https://www.ncbi.nlm.nih.gov/pubmed/22002306
http://dx.doi.org/10.1038/onc.2011.476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381367/
https://www.ncbi.nlm.nih.gov/pubmed/22002306
http://dx.doi.org/10.1038/onc.2011.476

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