Defined Folate-PEG-siRNA Conjugates for Receptor-specific Gene Silencing

Gene silencing mediated by small interfering RNA (siRNA) is a novel approach in the development of new cancer therapeutics. Polycations used for nucleic acid delivery still remain heterogeneous compounds, despite continuous progress in polymer synthetic technologies. Here we report the development o...

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Detalles Bibliográficos
Autores principales: Dohmen, Christian, Fröhlich, Thomas, Lächelt, Ulrich, Röhl, Ingo, Vornlocher, Hans-Peter, Hadwiger, Philipp, Wagner, Ernst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381594/
https://www.ncbi.nlm.nih.gov/pubmed/23344624
http://dx.doi.org/10.1038/mtna.2011.10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381594/
https://www.ncbi.nlm.nih.gov/pubmed/23344624
http://dx.doi.org/10.1038/mtna.2011.10

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