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TCR Signaling Emerges from the Sum of Many Parts

“How does T cell receptor signaling begin?” Answering this question requires an understanding of how the parts of the molecular machinery that mediates this process fit and work together. Ultimately this molecular architecture must (i) trigger the relay of information from the TCR-pMHC interface to...

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Detalles Bibliográficos
Autores principales: Kuhns, Michael S., Davis, Mark M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381686/
https://www.ncbi.nlm.nih.gov/pubmed/22737151
http://dx.doi.org/10.3389/fimmu.2012.00159