N-(phosphonacetyl)-L-aspartate induces TAp73-dependent apoptosis by modulating multiple Bcl-2 proteins: Potential for cancer therapy

p53 is essential for the cellular responses to DNA damage that help to maintain genomic stability. However, the great majority of human cancers undergo disruption of the p53-network. Identification and characterization of molecular components important in both p53-dependent and -independent apoptosi...

Descripción completa

Detalles Bibliográficos
Autores principales: Amin, A.R.M. Ruhul, Thakur, Vijay S, Gupta, Kalpana, Agarwal, Mukesh K, Wald, David N, Shin, Dong M, Agarwal, Munna L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382011/
https://www.ncbi.nlm.nih.gov/pubmed/22430213
http://dx.doi.org/10.1038/onc.2012.96

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382011/
https://www.ncbi.nlm.nih.gov/pubmed/22430213
http://dx.doi.org/10.1038/onc.2012.96

Ejemplares similares