Inhibition of Mitochondria- and Endoplasmic Reticulum Stress-Mediated Autophagy Augments Temozolomide-Induced Apoptosis in Glioma Cells

Autophagy is a crucial process for cells to maintain homeostasis and survival through degradation of cellular proteins and organelles, including mitochondria and endoplasmic reticula (ER). We previously demonstrated that temozolomide (TMZ), an alkylating agent for brain tumor chemotherapy, induced r...

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Detalles Bibliográficos
Autores principales: Lin, Chien-Ju, Lee, Chin-Cheng, Shih, Yung-Luen, Lin, Chien-Huang, Wang, Sheng-Hao, Chen, Thay-Hsiung, Shih, Chwen-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382156/
https://www.ncbi.nlm.nih.gov/pubmed/22745676
http://dx.doi.org/10.1371/journal.pone.0038706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382156/
https://www.ncbi.nlm.nih.gov/pubmed/22745676
http://dx.doi.org/10.1371/journal.pone.0038706

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