Fluorescence-Based Phenotypic Selection Allows Forward Genetic Screens in Haploid Human Cells

The isolation of haploid cell lines has recently allowed the power of forward genetic screens to be applied to mammalian cells. The interest in applying this powerful genetic approach to a mammalian system is only tempered by the limited utility of these screens, if confined to lethal phenotypes. He...

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Detalles Bibliográficos
Autores principales: Duncan, Lidia M., Timms, Richard T., Zavodszky, Eszter, Cano, Florencia, Dougan, Gordon, Randow, Felix, Lehner, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382162/
https://www.ncbi.nlm.nih.gov/pubmed/22745803
http://dx.doi.org/10.1371/journal.pone.0039651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382162/
https://www.ncbi.nlm.nih.gov/pubmed/22745803
http://dx.doi.org/10.1371/journal.pone.0039651

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