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Fluorescence-Based Phenotypic Selection Allows Forward Genetic Screens in Haploid Human Cells
The isolation of haploid cell lines has recently allowed the power of forward genetic screens to be applied to mammalian cells. The interest in applying this powerful genetic approach to a mammalian system is only tempered by the limited utility of these screens, if confined to lethal phenotypes. He...
Autores principales: | Duncan, Lidia M., Timms, Richard T., Zavodszky, Eszter, Cano, Florencia, Dougan, Gordon, Randow, Felix, Lehner, Paul J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382162/ https://www.ncbi.nlm.nih.gov/pubmed/22745803 http://dx.doi.org/10.1371/journal.pone.0039651 |
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