Investigation of D(1) Receptor–Agonist Interactions and D(1)/D(2) Agonist Selectivity Using a Combination of Pharmacophore and Receptor Homology Modeling

The aim of this study was to use a combined structure and pharmacophore modeling approach to extract information regarding dopamine D(1) receptor agonism and D(1)/D(2) agonist selectivity. A 3D structure model of the D(1) receptor in its agonist-bound state was constructed with a full D(1) agonist p...

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Detalles Bibliográficos
Autores principales: Malo, Marcus, Brive, Lars, Luthman, Kristina, Svensson, Peder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382191/
https://www.ncbi.nlm.nih.gov/pubmed/22315216
http://dx.doi.org/10.1002/cmdc.201100546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382191/
https://www.ncbi.nlm.nih.gov/pubmed/22315216
http://dx.doi.org/10.1002/cmdc.201100546

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