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Investigation of D(1) Receptor–Agonist Interactions and D(1)/D(2) Agonist Selectivity Using a Combination of Pharmacophore and Receptor Homology Modeling
The aim of this study was to use a combined structure and pharmacophore modeling approach to extract information regarding dopamine D(1) receptor agonism and D(1)/D(2) agonist selectivity. A 3D structure model of the D(1) receptor in its agonist-bound state was constructed with a full D(1) agonist p...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
WILEY-VCH Verlag
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382191/ https://www.ncbi.nlm.nih.gov/pubmed/22315216 http://dx.doi.org/10.1002/cmdc.201100546 |