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Linagliptin Improves Insulin Sensitivity and Hepatic Steatosis in Diet-Induced Obesity

Linagliptin (tradjenta™) is a selective dipeptidyl peptidase-4 (DPP-4) inhibitor. DPP-4 inhibition attenuates insulin resistance and improves peripheral glucose utilization in humans. However, the effects of chronic DPP-4 inhibition on insulin sensitivity are not known. The effects of long-term trea...

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Detalles Bibliográficos
Autores principales: Kern, Matthias, Klöting, Nora, Niessen, Heiko G., Thomas, Leo, Stiller, Detlef, Mark, Michael, Klein, Thomas, Blüher, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382200/
https://www.ncbi.nlm.nih.gov/pubmed/22761701
http://dx.doi.org/10.1371/journal.pone.0038744