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Linagliptin Improves Insulin Sensitivity and Hepatic Steatosis in Diet-Induced Obesity
Linagliptin (tradjenta™) is a selective dipeptidyl peptidase-4 (DPP-4) inhibitor. DPP-4 inhibition attenuates insulin resistance and improves peripheral glucose utilization in humans. However, the effects of chronic DPP-4 inhibition on insulin sensitivity are not known. The effects of long-term trea...
Autores principales: | Kern, Matthias, Klöting, Nora, Niessen, Heiko G., Thomas, Leo, Stiller, Detlef, Mark, Michael, Klein, Thomas, Blüher, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382200/ https://www.ncbi.nlm.nih.gov/pubmed/22761701 http://dx.doi.org/10.1371/journal.pone.0038744 |
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