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Proteolytic Processing of ErbB4 in Breast Cancer

ErbB4 is a receptor tyrosine kinase that can signal by a mechanism involving proteolytic release of intracellular and extracellular receptor fragments. Proteolysis-dependent signaling of ErbB4 has been proposed to be enhanced in breast cancer, mainly based on immunohistochemical localization of intr...

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Detalles Bibliográficos
Autores principales: Hollmén, Maija, Liu, Ping, Kurppa, Kari, Wildiers, Hans, Reinvall, Irene, Vandorpe, Thijs, Smeets, Ann, Deraedt, Karen, Vahlberg, Tero, Joensuu, Heikki, Leahy, Daniel J., Schöffski, Patrick, Elenius, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382207/
https://www.ncbi.nlm.nih.gov/pubmed/22761786
http://dx.doi.org/10.1371/journal.pone.0039413