PD-1 Blockage Reverses Immune Dysfunction and Hepatitis B Viral Persistence in a Mouse Animal Model

Persistent hepatitis B viral (HBV) infection results in chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma (HCC). Recent studies in animal models of viral infection indicate that the interaction between the inhibitory receptor, programmed death (PD)-1, on lymphocytes and its ligand (PD...

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Detalles Bibliográficos
Autores principales: Tzeng, Horng-Tay, Tsai, Hwei-Fang, Liao, Hsiu-Jung, Lin, Yi-Jiun, Chen, Lieping, Chen, Pei-Jer, Hsu, Ping-Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382233/
https://www.ncbi.nlm.nih.gov/pubmed/22761734
http://dx.doi.org/10.1371/journal.pone.0039179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382233/
https://www.ncbi.nlm.nih.gov/pubmed/22761734
http://dx.doi.org/10.1371/journal.pone.0039179

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