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Cooperativity among Short Amyloid Stretches in Long Amyloidogenic Sequences

Amyloid fibrillar aggregates of polypeptides are associated with many neurodegenerative diseases. Short peptide segments in protein sequences may trigger aggregation. Identifying these stretches and examining their behavior in longer protein segments is critical for understanding these diseases and...

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Detalles Bibliográficos
Autores principales: Hu, Lele, Cui, Weiren, He, Zhisong, Shi, Xiaohe, Feng, Kaiyan, Ma, Buyong, Cai, Yu-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382238/
https://www.ncbi.nlm.nih.gov/pubmed/22761773
http://dx.doi.org/10.1371/journal.pone.0039369