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Biologic Therapy in Head and Neck Cancer: A Road with Hurdles
The epidermal growth factor receptor (EGFR) is overexpressed in the vast majority of cases of squamous cell carcinoma of the head and neck (SCCHN). A high EGFR expression is associated with an unfavorable prognosis. Cetuximab is a chimeric human/murine IgG1 antibody which binds with high affinity to...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scholarly Research Network
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382358/ https://www.ncbi.nlm.nih.gov/pubmed/22745915 http://dx.doi.org/10.5402/2012/163752 |