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Biologic Therapy in Head and Neck Cancer: A Road with Hurdles

The epidermal growth factor receptor (EGFR) is overexpressed in the vast majority of cases of squamous cell carcinoma of the head and neck (SCCHN). A high EGFR expression is associated with an unfavorable prognosis. Cetuximab is a chimeric human/murine IgG1 antibody which binds with high affinity to...

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Detalles Bibliográficos
Autores principales: Specenier, Pol, Vermorken, Jan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382358/
https://www.ncbi.nlm.nih.gov/pubmed/22745915
http://dx.doi.org/10.5402/2012/163752