Phospholipogenic Pharmaceuticals Are Associated with a Higher Incidence of Histological Findings than Nonphospholipogenic Pharmaceuticals in Preclinical Toxicology Studies

While phospholipidosis is thought to be an adaptive response to chemical challenge, many phospholipogenic compounds are known to display adverse effects in preclinical species and humans. To investigate the link between phospholipogenic administration and incidence of preclinical histological signal...

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Detalles Bibliográficos
Autores principales: Barone, Linda R., Boyer, Scott, Damewood, James R., Fikes, James, Ciaccio, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382391/
https://www.ncbi.nlm.nih.gov/pubmed/22745636
http://dx.doi.org/10.1155/2012/308594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382391/
https://www.ncbi.nlm.nih.gov/pubmed/22745636
http://dx.doi.org/10.1155/2012/308594

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