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Histone Deacetylases Regulate Gonadotropin-Releasing Hormone I Gene Expression via Modulating Otx2-Driven Transcriptional Activity

BACKGROUND: Precise coordination of the hypothalamic-pituitary-gonadal axis orchestrates the normal reproductive function. As a central regulator, the appropriate synthesis and secretion of gonadotropin-releasing hormone I (GnRH-I) from the hypothalamus is essential for the coordination. Recently, e...

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Detalles Bibliográficos
Autores principales: Gan, Lu, Ni, Pei-Yan, Ge, Yan, Xiao, Yun-Fei, Sun, Chang-Yan, Deng, Lin, Zhang, Wei, Wu, Si-Si, Liu, Ying, Jiang, Wei, Xin, Hong-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382570/
https://www.ncbi.nlm.nih.gov/pubmed/22761896
http://dx.doi.org/10.1371/journal.pone.0039770