Different Pattern of Immunoglobulin Gene Usage by HIV-1 Compared to Non-HIV-1 Antibodies Derived from the Same Infected Subject

A biased usage of immunoglobulin (Ig) genes is observed in human anti-HIV-1 monoclonal antibodies (mAbs) resulting probably from compensation to reduced usage of the VH3 family genes, while the other alternative suggests that this bias usage is due to antigen requirements. If the antigen structure i...

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Detalles Bibliográficos
Autores principales: Li, Liuzhe, Wang, Xiao-Hong, Banerjee, Sagarika, Volsky, Barbara, Williams, Constance, Virland, Diana, Nadas, Arthur, Seaman, Michael S., Chen, Xuemin, Spearman, Paul, Zolla-Pazner, Susan, Gorny, Miroslaw K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382572/
https://www.ncbi.nlm.nih.gov/pubmed/22761815
http://dx.doi.org/10.1371/journal.pone.0039534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382572/
https://www.ncbi.nlm.nih.gov/pubmed/22761815
http://dx.doi.org/10.1371/journal.pone.0039534

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