β-Catenin Loss in Hepatocytes Promotes Hepatocellular Cancer after Diethylnitrosamine and Phenobarbital Administration to Mice

Hepatocellular Carcinoma (HCC) is the fifth most common cancer worldwide. β-Catenin, the central orchestrator of the canonical Wnt pathway and a known oncogene is paramount in HCC pathogenesis. Administration of phenobarbital (PB) containing water (0.05% w/v) as tumor promoter following initial inje...

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Detalles Bibliográficos
Autores principales: Awuah, Prince Kwaku, Rhieu, Byung Han, Singh, Sucha, Misse, Amalea, Monga, Satdarshan P. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382575/
https://www.ncbi.nlm.nih.gov/pubmed/22761897
http://dx.doi.org/10.1371/journal.pone.0039771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382575/
https://www.ncbi.nlm.nih.gov/pubmed/22761897
http://dx.doi.org/10.1371/journal.pone.0039771

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