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Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Impairs G2 Checkpoint in Human Nasopharyngeal Epithelial Cells through Defective Chk1 Activation

Nasopharyngeal carcinoma (NPC) is a common cancer in Southeast Asia, particularly in southern regions of China. EBV infection is closely associated with NPC and has long been postulated to play an etiological role in the development of NPC. However, the role of EBV in malignant transformation of nas...

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Detalles Bibliográficos
Autores principales: Deng, Wen, Pang, Pei Shin, Tsang, Chi Man, Hau, Pok Man, Yip, Yim Ling, Cheung, Annie L. M., Tsao, Sai Wah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382577/
https://www.ncbi.nlm.nih.gov/pubmed/22761726
http://dx.doi.org/10.1371/journal.pone.0039095