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Blocking Fibroblast Growth Factor Receptor Signaling Inhibits Tumor Growth, Lymphangiogenesis, and Metastasis

Fibroblast Growth Factor receptor (FGFR) activity plays crucial roles in tumor growth and patient survival. However, FGF (Fibroblast Growth Factor) signaling as a target for cancer therapy has been under-investigated compared to other receptor tyrosine kinases. Here, we studied the effect of FGFR si...

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Detalles Bibliográficos
Autores principales: Larrieu-Lahargue, Frédéric, Welm, Alana L., Bouchecareilh, Marion, Alitalo, Kari, Li, Dean Y., Bikfalvi, Andreas, Auguste, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382584/
https://www.ncbi.nlm.nih.gov/pubmed/22761819
http://dx.doi.org/10.1371/journal.pone.0039540