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Blocking Fibroblast Growth Factor Receptor Signaling Inhibits Tumor Growth, Lymphangiogenesis, and Metastasis
Fibroblast Growth Factor receptor (FGFR) activity plays crucial roles in tumor growth and patient survival. However, FGF (Fibroblast Growth Factor) signaling as a target for cancer therapy has been under-investigated compared to other receptor tyrosine kinases. Here, we studied the effect of FGFR si...
Autores principales: | Larrieu-Lahargue, Frédéric, Welm, Alana L., Bouchecareilh, Marion, Alitalo, Kari, Li, Dean Y., Bikfalvi, Andreas, Auguste, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382584/ https://www.ncbi.nlm.nih.gov/pubmed/22761819 http://dx.doi.org/10.1371/journal.pone.0039540 |
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