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Progranulin as a Prognostic Biomarker for Breast Cancer Recurrence in Patients Who Had Hormone Receptor-Positive Tumors: A Cohort Study

BACKGROUND: Progranulin (PGRN) is considered to play an important role in breast cancer tumorigenesis and in inhibiting tamoxifen-induced apoptosis. We aimed to determine whether PGRN levels are associated with breast cancer recurrence after curative surgery. METHODOLOGY/PRINCIPAL FINDINGS: We evalu...

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Detalles Bibliográficos
Autores principales: Koo, Dong Hoe, Park, Cheol-Young, Lee, Eun Sook, Ro, Jungsil, Oh, Sang Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382586/
https://www.ncbi.nlm.nih.gov/pubmed/22761921
http://dx.doi.org/10.1371/journal.pone.0039880