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Loss of Hairless Confers Susceptibility to UVB-Induced Tumorigenesis via Disruption of NF-kappaB Signaling

In order to model squamous cell carcinoma development in vivo, researchers have long preferred hairless mouse models such as SKH-1 mice that have traditionally been classified as ‘wild-type’ mice irrespective of the genetic factors underlying their hairless phenotype. The work presented here shows t...

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Detalles Bibliográficos
Autores principales: Kim, Hyunmi, Casta, Alexandre, Tang, Xiuwei, Luke, Courtney T., Kim, Arianna L., Bickers, David R., Athar, Mohammad, Christiano, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382590/
https://www.ncbi.nlm.nih.gov/pubmed/22761871
http://dx.doi.org/10.1371/journal.pone.0039691