Peroxiredoxin 3 Is a Redox-Dependent Target of Thiostrepton in Malignant Mesothelioma Cells

Thiostrepton (TS) is a thiazole antibiotic that inhibits expression of FOXM1, an oncogenic transcription factor required for cell cycle progression and resistance to oncogene-induced oxidative stress. The mechanism of action of TS is unclear and strategies that enhance TS activity will improve its t...

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Detalles Bibliográficos
Autores principales: Newick, Kheng, Cunniff, Brian, Preston, Kelsey, Held, Paul, Arbiser, Jack, Pass, Harvey, Mossman, Brooke, Shukla, Arti, Heintz, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382597/
https://www.ncbi.nlm.nih.gov/pubmed/22761781
http://dx.doi.org/10.1371/journal.pone.0039404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382597/
https://www.ncbi.nlm.nih.gov/pubmed/22761781
http://dx.doi.org/10.1371/journal.pone.0039404

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