Immunotoxin-Mediated Tract Targeting in the Primate Brain: Selective Elimination of the Cortico-Subthalamic “Hyperdirect” Pathway

Using a neuron-specific retrograde gene-transfer vector (NeuRet vector), we established immunotoxin (IT)-mediated tract targeting in the primate brain that allows ablation of a neuronal population constituting a particular pathway. Here, we attempted selective removal of the cortico-subthalamic “hyp...

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Detalles Bibliográficos
Autores principales: Inoue, Ken-ichi, Koketsu, Daisuke, Kato, Shigeki, Kobayashi, Kazuto, Nambu, Atsushi, Takada, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382612/
https://www.ncbi.nlm.nih.gov/pubmed/22761729
http://dx.doi.org/10.1371/journal.pone.0039149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382612/
https://www.ncbi.nlm.nih.gov/pubmed/22761729
http://dx.doi.org/10.1371/journal.pone.0039149

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