Inhibition of CLIC4 Enhances Autophagy and Triggers Mitochondrial and ER Stress-Induced Apoptosis in Human Glioma U251 Cells under Starvation

CLIC4/mtCLIC, a chloride intracellular channel protein, localizes to mitochondria, endoplasmic reticulum (ER), nucleus and cytoplasm, and participates in the apoptotic response to stress. Apoptosis and autophagy, the main types of the programmed cell death, seem interconnected under certain stress c...

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Detalles Bibliográficos
Autores principales: Zhong, Jiateng, Kong, Xiaoxia, Zhang, Hongyu, Yu, Chunyan, Xu, Ye, Kang, Jinsong, Yu, Huimei, Yi, Haowei, Yang, Xiaochun, Sun, Liankun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382619/
https://www.ncbi.nlm.nih.gov/pubmed/22761775
http://dx.doi.org/10.1371/journal.pone.0039378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382619/
https://www.ncbi.nlm.nih.gov/pubmed/22761775
http://dx.doi.org/10.1371/journal.pone.0039378

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