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The Ecology of Antibiotic Use in the ICU: Homogeneous Prescribing of Cefepime but Not Tazocin Selects for Antibiotic Resistant Infection

BACKGROUND: Antibiotic homogeneity is thought to drive resistance but in vivo data are lacking. In this study, we determined the impact of antibiotic homogeneity per se, and of cefepime versus antipseudomonal penicillin/β-lactamase inhibitor combinations (APP-β), on the likelihood of infection or co...

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Detalles Bibliográficos
Autores principales: Ginn, Andrew N., Wiklendt, Agnieszka M., Gidding, Heather F., George, Narelle, O’Driscoll, James S., Partridge, Sally R., O’Toole, Brian I., Perri, Rita A., Faoagali, Joan, Gallagher, John E., Lipman, Jeffrey, Iredell, Jonathan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382621/
https://www.ncbi.nlm.nih.gov/pubmed/22761698
http://dx.doi.org/10.1371/journal.pone.0038719