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The Ecology of Antibiotic Use in the ICU: Homogeneous Prescribing of Cefepime but Not Tazocin Selects for Antibiotic Resistant Infection
BACKGROUND: Antibiotic homogeneity is thought to drive resistance but in vivo data are lacking. In this study, we determined the impact of antibiotic homogeneity per se, and of cefepime versus antipseudomonal penicillin/β-lactamase inhibitor combinations (APP-β), on the likelihood of infection or co...
Autores principales: | Ginn, Andrew N., Wiklendt, Agnieszka M., Gidding, Heather F., George, Narelle, O’Driscoll, James S., Partridge, Sally R., O’Toole, Brian I., Perri, Rita A., Faoagali, Joan, Gallagher, John E., Lipman, Jeffrey, Iredell, Jonathan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382621/ https://www.ncbi.nlm.nih.gov/pubmed/22761698 http://dx.doi.org/10.1371/journal.pone.0038719 |
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