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Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation

BACKGROUND: HIV-1 Nef protein contributes to pathogenesis via multiple functions that include enhancement of viral replication and infectivity, alteration of intracellular trafficking, and modulation of cellular signaling pathways. Nef stimulates formation of tunneling nanotubes and virological syna...

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Detalles Bibliográficos
Autores principales: Mukerji, Joya, Olivieri, Kevin C, Misra, Vikas, Agopian, Kristin A, Gabuzda, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382630/
https://www.ncbi.nlm.nih.gov/pubmed/22534017
http://dx.doi.org/10.1186/1742-4690-9-33