Cargando…

Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation

BACKGROUND: HIV-1 Nef protein contributes to pathogenesis via multiple functions that include enhancement of viral replication and infectivity, alteration of intracellular trafficking, and modulation of cellular signaling pathways. Nef stimulates formation of tunneling nanotubes and virological syna...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mukerji, Joya, Olivieri, Kevin C, Misra, Vikas, Agopian, Kristin A, Gabuzda, Dana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382630/ https://www.ncbi.nlm.nih.gov/pubmed/22534017 http://dx.doi.org/10.1186/1742-4690-9-33

Ejemplares similares

Nef-mediated enhancement of cellular activation and human immunodeficiency virus type 1 replication in primary T cells is dependent on association with p21-activated kinase 2
por: Olivieri, Kevin C, et al.
Publicado: (2011)

Association with PAK2 Enables Functional Interactions of Lentiviral Nef Proteins with the Exocyst Complex
por: Imle, Andrea, et al.
Publicado: (2015)

Exosomes Are Unlikely Involved in Intercellular Nef Transfer
por: Luo, Xiaoyu, et al.
Publicado: (2015)

Cerebrospinal fluid extracellular vesicles and neurofilament light protein as biomarkers of central nervous system injury in HIV-infected patients on antiretroviral therapy
por: Guha, Debjani, et al.
Publicado: (2019)

Proteomic analysis of cerebrospinal fluid extracellular vesicles reveals synaptic injury, inflammation, and stress response markers in HIV patients with cognitive impairment
por: Guha, Debjani, et al.
Publicado: (2019)

Macrophage polarization impacts tunneling nanotube formation and intercellular organelle trafficking
por: Goodman, Spencer, et al.
Publicado: (2019)

Transcriptomic analysis of monocytes from HIV-positive men on antiretroviral therapy reveals effects of tobacco smoking on interferon and stress response systems associated with depressive symptoms
por: Lorenz, David R., et al.
Publicado: (2019)

Applications and Limitations of Inflammatory Biomarkers for Studies on Neurocognitive Impairment in HIV Infection
por: Cassol, Edana, et al.
Publicado: (2013)

CSF Inflammation Markers Associated with Asymptomatic Viral Escape in Cerebrospinal Fluid of HIV-Positive Individuals on Antiretroviral Therapy
por: Guha, Debjani, et al.
Publicado: (2023)

Impact of Antiretroviral Regimens on Cerebrospinal Fluid Viral Escape in a Prospective Multicohort Study of Antiretroviral Therapy-Experienced Human Immunodeficiency Virus-1–Infected Adults in the United States
por: Mukerji, Shibani S, et al.
Publicado: (2018)

An exocyst component, Sec5, is essential for ascospore formation in Bipolaris maydis
por: Tsuji, Kenya, et al.
Publicado: (2021)

Lipid Profiles and APOE4 Allele Impact Midlife Cognitive Decline in HIV-Infected Men on Antiretroviral Therapy
por: Mukerji, Shibani S., et al.
Publicado: (2016)

The Exocyst Complex in Health and Disease
por: Martin-Urdiroz, Magdalena, et al.
Publicado: (2016)

The exocyst complex in neurological disorders
por: Halim, Dilara O., et al.
Publicado: (2023)

Nef-mediated Clathrin-coated Pit Formation
por: Foti, Michelangelo, et al.
Publicado: (1997)

Multifaceted Roles of Tunneling Nanotubes in Intercellular Communication
por: Marzo, Ludovica, et al.
Publicado: (2012)

Intercellular Communication in the Brain through Tunneling Nanotubes
por: Khattar, Khattar E., et al.
Publicado: (2022)

Cerebrospinal fluid metabolomics reveals altered waste clearance and accelerated aging in HIV patients with neurocognitive impairment
por: Cassol, Edana, et al.
Publicado: (2014)

Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo
por: Gorry, Paul R, et al.
Publicado: (2007)

Old AIMs of the exocyst: evidence for an ancestral association of exocyst subunits with autophagy-associated Atg8 proteins
por: Cvrčková, Fatima, et al.
Publicado: (2013)

Regulation of Exocyst Function in Pollen Tube Growth by Phosphorylation of Exocyst Subunit EXO70C2
por: Saccomanno, Antonietta, et al.
Publicado: (2021)

A single β-octyl glucoside molecule induces HIV-1 Nef dimer formation in the absence of partner protein binding
por: Wu, Mousheng, et al.
Publicado: (2018)

Low Neuroactive Steroids Identifies a Biological Subtype of Depression in Adults with Human Immunodeficiency Virus on Suppressive Antiretroviral Therapy
por: Mukerji, Shibani S, et al.
Publicado: (2020)

Increased risk of anal squamous cell carcinoma in HIV-positive men with prior hepatitis B virus infection
por: Aldersley, Jordan, et al.
Publicado: (2019)

Intact Proviral DNA Analysis of the Brain Viral Reservoir and Relationship to Neuroinflammation in People with HIV on Suppressive Antiretroviral Therapy
por: Gabuzda, Dana, et al.
Publicado: (2023)

Exocyst finds way without Rho
por: LeBrasseur, Nicole
Publicado: (2005)

Evolution of the Land Plant Exocyst Complexes
por: Cvrčková, Fatima, et al.
Publicado: (2012)

The Function of the Exocyst is Regulated by Effector Phosphorylation
por: Chen, Xiao-Wei, et al.
Publicado: (2011)

The exocyst and regulatory GTPases in urinary exosomes
por: Chacon‐Heszele, Maria F., et al.
Publicado: (2014)

Cryo-EM Structure of the Exocyst Complex
por: Mei, Kunrong, et al.
Publicado: (2018)

Relevance of the Exocyst in Arabidopsis exo70e2 Mutant for Cellular Homeostasis under Stress
por: Neves, João, et al.
Publicado: (2022)

Correction: A single β-octyl glucoside molecule induces HIV-1 Nef dimer formation in the absence of partner protein binding
Publicado: (2018)

Tunneling Nanotubes Provide a Unique Conduit for Intercellular Transfer of Cellular Contents in Human Malignant Pleural Mesothelioma
por: Lou, Emil, et al.
Publicado: (2012)

Plasma metabolomics identifies lipid abnormalities linked to markers of inflammation, microbial translocation, and hepatic function in HIV patients receiving protease inhibitors
por: Cassol, Edana, et al.
Publicado: (2013)

Small RNA sequencing of extracellular vesicles identifies circulating miRNAs related to inflammation and oxidative stress in HIV patients
por: Chettimada, Sukrutha, et al.
Publicado: (2020)

Vascular injury markers associated with cognitive impairment in people with HIV on suppressive antiretroviral therapy
por: Guha, Debjani, et al.
Publicado: (2023)

Comparative proteomics of wild-type and nef-deleted HIV-1 particles
por: Brégnard, Christelle, et al.
Publicado: (2011)

Structural basis of evasion of cellular adaptive immunity by HIV-1 Nef
por: Jia, Xiaofei, et al.
Publicado: (2012)

Novel role of HIV-1 Nef in regulating the ubiquitination of cellular proteins
por: Ghaly, Maria, et al.
Publicado: (2023)

Exocyst proteins in cytokinesis: Regulation by Rab11
por: Neto, Hélia, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_li8l8neul7v9va1bcjgt603i54