Distinct subunit contributions to the activation of M-type potassium channels by PI(4,5)P(2)

Low-threshold voltage-gated M-type potassium channels (M channels) are tetraheteromers, commonly of two Kv7.2 and two Kv7.3 subunits. Though gated by voltage, the channels have an absolute requirement for binding of the membrane phospholipid phosphatidylinositol-4,5-bisphosphate (PI(4,5)P(2)) to ope...

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Detalles Bibliográficos
Autores principales: Telezhkin, Vsevolod, Brown, David A., Gibb, Alasdair J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382723/
https://www.ncbi.nlm.nih.gov/pubmed/22689829
http://dx.doi.org/10.1085/jgp.201210796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382723/
https://www.ncbi.nlm.nih.gov/pubmed/22689829
http://dx.doi.org/10.1085/jgp.201210796

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