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The Three Dimensional Quantitative Structure Activity Relationships (3D-QSAR) and Docking Studies of Curcumin Derivatives as Androgen Receptor Antagonists

Androgen receptor antagonists have been proved to be effective anti-prostate cancer agents. 3D-QSAR and Molecular docking methods were performed on curcumin derivatives as androgen receptor antagonists. The bioactive conformation was explored by docking the potent compound 29 into the binding site o...

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Detalles Bibliográficos
Autores principales: Xu, Guanhong, Chu, Yanyan, Jiang, Nan, Yang, Jing, Li, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382773/
https://www.ncbi.nlm.nih.gov/pubmed/22754355
http://dx.doi.org/10.3390/ijms13056138