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Anti-Proliferation and Anti-Invasion Effects of Diosgenin on Gastric Cancer BGC-823 Cells with HIF-1α shRNAs

Drug resistance is a major factor for the limited efficacy of chemotherapy in gastric cancer treatment. Hypoxia-inducible factor-1α (HIF-1α), a central transcriptional factor in hypoxia, is suggested to participate in the resistance. Here, we identified a hypoxia-mimic (cobalt chloride) sensitive ga...

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Detalles Bibliográficos
Autores principales: Mao, Zhu-Jun, Tang, Qian-Jue, Zhang, Ci-An, Qin, Zhi-Feng, Pang, Bin, Wei, Pin-kang, Liu, Bo, Chou, Yuan-Neng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382793/
https://www.ncbi.nlm.nih.gov/pubmed/22754381
http://dx.doi.org/10.3390/ijms13056521