Development of immune memory to glial brain tumors after tumor regression induced by immunotherapeutic Toll-like receptor 7/8 activation

The efficacy of immunotherapeutic TLR7/8 activation by resiquimod (R848) was evaluated in vivo, in the CNS-1 rat glioma model syngeneic to Lewis rats. The immune treatment was compared with cytotoxic cyclophosphamide chemotherapy, and as well, was compared with the combination cytotoxic and immunoth...

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Detalles Bibliográficos
Autores principales: Stathopoulos, Apostolis, Pretto, Chrystel, Devillers, Laurent, Pierre, Denis, Hofman, Florence M., Kruse, Carol, Jadus, Martin, Chen, Thomas C., Schijns, Virgil E.J.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382858/
https://www.ncbi.nlm.nih.gov/pubmed/22737605
http://dx.doi.org/10.4161/onci.19068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382858/
https://www.ncbi.nlm.nih.gov/pubmed/22737605
http://dx.doi.org/10.4161/onci.19068

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