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Targeting cancer stem cells with ALDH1A1-based immunotherapy
ALDH(bright) cells in human tumor cells lines, xenografts and lesions have been shown to have characteristics of cancer stem cells (CSC). We have shown that these cells are recognized by ALDH1A1-specific CD8(+) T cells in vitro and in vivo. The results support the potential of ALDH1A1-based immunoth...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382868/ https://www.ncbi.nlm.nih.gov/pubmed/22737624 http://dx.doi.org/10.4161/onci.18826 |