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Subversion of the chemotherapy-induced anticancer immune response by the ecto-ATPase CD39

The efficacy of antineoplastic chemotherapies with anthracyclines or oxaliplatin relies on the induction of immunogenic cell death, thus provoking an anticancer immune response. Recently, we observed that overexpression of CD39, an ATP-degrading enzyme expressed on the cell surface, abolishes the im...

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Detalles Bibliográficos
Autores principales: Michaud, Mickaël, Sukkurwala, Abdul Qader, Martins, Isabelle, Shen, Shensi, Zitvogel, Laurence, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382873/
https://www.ncbi.nlm.nih.gov/pubmed/22737627
http://dx.doi.org/10.4161/onci.19070