Cargando…
IRF-1 is critical for IFNγ mediated immune surveillance
We recently described that IRF-1 is important for IFNγ mediated immune surveillance in metastasis. Despite the upregulation of MHC Class I in tumor cells, IRF-1 leads to a NK cell-dependent elimination of tumor cells. This mechanism is independent on inhibitory receptors and cytotoxic granules but d...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382888/ https://www.ncbi.nlm.nih.gov/pubmed/22754776 |