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Immuno-targeting of pancreatic cancer stem cells: A new therapeutic strategy against a devastating disease?

Pancreatic cancer is a highly aggressive and deadly disease harboring a distinct population of cancer stem cells (CSC) that is not affected by conventional therapies. A new therapeutic approach using the EpCAM/CD3-bispecific antibody MT110 is capable of activating and redirecting cytotoxic T cells t...

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Detalles Bibliográficos
Autores principales: Cioffi, Michele, Heeschen, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382890/
https://www.ncbi.nlm.nih.gov/pubmed/22754787