Pro-survival signaling via CD27 costimulation drives effective CAR T-cell therapy

The impact of CD27 costimulation on human T lymphocyte effector function and memory formation has been limited to evaluations using in vitro cell culture systems and observations from the clinic. We therefore investigated whether CD27 signaling augments antigen redirected human T-cell survival, expa...

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Detalles Bibliográficos
Autores principales: Song, De-Gang, Powell, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382904/
https://www.ncbi.nlm.nih.gov/pubmed/22754782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382904/
https://www.ncbi.nlm.nih.gov/pubmed/22754782

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