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Induction of Cellular Immune Response by DNA Vaccine Coexpressing E. acervulina 3-1E Gene and Mature CHIl-15 Gene

We previously reported that the chimeric DNA vaccine pcDNA-3-1E-linker-mChIL-15, fused through linking Eimeria acervulina 3-1E encoding gene and mature chicken IL-15 (mChIL-15) gene with four flexible amino acid SPGS, could significantly offer protection against homologous challenge. In the present...

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Detalles Bibliográficos
Autores principales: Ma, Dexing, Ma, Chunli, Gao, Mingyang, Li, Guangxing, Niu, Ze, Huang, Xiaodan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382946/
https://www.ncbi.nlm.nih.gov/pubmed/22754694
http://dx.doi.org/10.1155/2012/654279