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Myeloid Heme Oxygenase-1 Haploinsufficiency Reduces High Fat Diet-Induced Insulin Resistance by Affecting Adipose Macrophage Infiltration in Mice

Increased adipose tissue macrophages contribute to obesity-induced metabolic syndrome. Heme oxygenase-1 (HO-1) is a stress-inducible enzyme with potent anti-inflammatory and proangiogenic activities in macrophages. However, the role of macrophage HO-1 on obesity-induced adipose inflammation and meta...

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Detalles Bibliográficos
Autores principales: Huang, Jun-Yuan, Chiang, Ming-Tsai, Yet, Shaw-Fang, Chau, Lee-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382977/
https://www.ncbi.nlm.nih.gov/pubmed/22761690
http://dx.doi.org/10.1371/journal.pone.0038626