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Catalytic Transitions in the Human MDR1 P-Glycoprotein Drug Binding Sites
[Image: see text] Multidrug resistance proteins that belong to the ATP-binding cassette family like the human P-glycoprotein (ABCB1 or Pgp) are responsible for many failed cancer and antiviral chemotherapies because these membrane transporters remove the chemotherapeutics from the targeted cells. Un...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383123/ https://www.ncbi.nlm.nih.gov/pubmed/22647192 http://dx.doi.org/10.1021/bi300299z |