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Impact of N-Terminal Acetylation of α-Synuclein on Its Random Coil and Lipid Binding Properties

[Image: see text] N-Terminal acetylation of α-synuclein (aS), a protein implicated in the etiology of Parkinson’s disease, is common in mammals. The impact of this modification on the protein’s structure and dynamics in free solution and on its membrane binding properties has been evaluated by high-...

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Detalles Bibliográficos
Autores principales: Maltsev, Alexander S., Ying, Jinfa, Bax, Ad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383124/
https://www.ncbi.nlm.nih.gov/pubmed/22694188
http://dx.doi.org/10.1021/bi300642h