Identification and Characterization of an Oxidative Degradation Product of Fexofenadine, Development and Validation of a Stability-Indicating RP-UPLC Method for the Estimation of Process Related Impurities and Degradation Products of Fexofenadine in Pharmaceutical Formulations

A novel stability-indicating gradient RP-UPLC method was developed for the quantitative determination of process related impurities and forced degradation products of fexofenadine HCl in pharmaceutical formulations. The method was developed by using Waters Aquity BEH C18 (100 mm x 2.1 mm) 1.7 μm col...

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Detalles Bibliográficos
Autores principales: Vaghela, Bhupendrasinh, Rao, Surendra Singh, Reddy, Annarapu Malleshwar, Venkatesh, Panuganti, Kumar, Navneet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383222/
https://www.ncbi.nlm.nih.gov/pubmed/22896817
http://dx.doi.org/10.3797/scipharm.1111-07

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383222/
https://www.ncbi.nlm.nih.gov/pubmed/22896817
http://dx.doi.org/10.3797/scipharm.1111-07

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