Cargando…

Identification and Characterization of an Oxidative Degradation Product of Fexofenadine, Development and Validation of a Stability-Indicating RP-UPLC Method for the Estimation of Process Related Impurities and Degradation Products of Fexofenadine in Pharmaceutical Formulations

A novel stability-indicating gradient RP-UPLC method was developed for the quantitative determination of process related impurities and forced degradation products of fexofenadine HCl in pharmaceutical formulations. The method was developed by using Waters Aquity BEH C18 (100 mm x 2.1 mm) 1.7 μm col...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vaghela, Bhupendrasinh, Rao, Surendra Singh, Reddy, Annarapu Malleshwar, Venkatesh, Panuganti, Kumar, Navneet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Österreichische Apotheker-Verlagsgesellschaft 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383222/ https://www.ncbi.nlm.nih.gov/pubmed/22896817 http://dx.doi.org/10.3797/scipharm.1111-07

Ejemplares similares

Fexofenadine-Induced Urticaria
por: Lee, Sang Woo, et al.
Publicado: (2011)

Development of validated stability-indicating chromatographic method for the determination of fexofenadine hydrochloride and its related impurities in pharmaceutical tablets
por: Maher, Hadir M, et al.
Publicado: (2011)

Development and Validation of a Stability-Indicating RP-HPLC Method for the Determination of Process-Related Impurities and Degradation Products of Rabeprazole Sodium in Pharmaceutical Formulation
por: Kumar, Navneet, et al.
Publicado: (2013)

Development and validation of a reverse phase-liquid chromatographic method for the estimation of butylated hydroxytoluene as antioxidant in paricalcitol hard gelatin capsule formulation dosage form
por: Vaghela, Bhupendrasinh, et al.
Publicado: (2011)

Study of the Complexation Behaviour of Fexofenadine with β-Cyclodextrin
por: Sapkal, Nidhi P., et al.
Publicado: (2010)

Fexofenadine in higher doses in chronic spontaneous urticaria
por: Godse, Kiran V., et al.
Publicado: (2010)

Acute Generalized Exanthematous Pustulosis Induced by Fexofenadine
por: Gupta, Tanvi, et al.
Publicado: (2016)

Restless legs syndrome induced by fexofenadine/pseudoephedrine
por: Nishioka, Hiroaki, et al.
Publicado: (2020)

Taste Masked Orodispersible Formulation of Fexofenadine Hydrochloride Using Ion Exchange Resins
por: Suares, Divya, et al.
Publicado: (2015)

QTc interval prolongation by fexofenadine in healthy human volunteers and its correlation with plasma levels of fexofenadine: A demonstration of anticlockwise hysteresis
por: Vyas, Falgun I., et al.
Publicado: (2010)

Fexofenadine hydrochloride in the treatment of allergic disease: a review
por: Axelrod, David, et al.
Publicado: (2008)

Fast Dissolving Tablets of Fexofenadine HCl by Effervescent Method
por: Nagendrakumar, D., et al.
Publicado: (2009)

Update meta-analysis on the efficacy and safety issues of fexofenadine
por: Gómez, René Maximiliano, et al.
Publicado: (2023)

Effects of Danshen Ethanol Extract on the Pharmacokinetics of Fexofenadine in Healthy Volunteers
por: Qiu, Furong, et al.
Publicado: (2014)

Effect of fexofenadine hydrochloride on allergic rhinitis aggravated by air pollutants
por: Ellis, Anne K., et al.
Publicado: (2021)

Stability-indicating HPLC Method for Simultaneous Determination of Montelukast and Fexofenadine Hydrochloride
por: Pankhaniya, Mona, et al.
Publicado: (2013)

Fexofenadine Suppresses Delayed-Type Hypersensitivity in the Murine Model of Palladium Allergy
por: Matsubara, Ryota, et al.
Publicado: (2017)

Effect of Rumex Acetosa Extract, a Herbal Drug, on the Absorption of Fexofenadine
por: Ahn, Jung Hwan, et al.
Publicado: (2020)

Interaction between Fexofenadine and CYP Phenotyping Probe Drugs in Geneva Cocktail
por: Bosilkovska, Marija, et al.
Publicado: (2019)

Fexofenadine: review of safety, efficacy and unmet needs in children with allergic rhinitis
por: Meltzer, Eli O., et al.
Publicado: (2021)

Fexofenadine Protects Against Intervertebral Disc Degeneration Through TNF Signaling
por: Liu, Kaiwen, et al.
Publicado: (2021)

Insights into urticaria in pediatric and adult populations and its management with fexofenadine hydrochloride
por: Ansotegui, Ignacio J., et al.
Publicado: (2022)

Cubosomes for Enhancing Intestinal Absorption of Fexofenadine Hydrochloride: In situ and in vivo Investigation
por: Sultan, Amal A, et al.
Publicado: (2022)

A novel validated stability indicating high performance liquid chromatographic method for estimation of degradation behavior of ciprofloxacin and tinidazole in solid oral dosage
por: Vaghela, Bhupendrasinh K., et al.
Publicado: (2013)

Assessing satisfaction with desloratadine and fexofenadine in allergy patients who report dissatisfaction with loratadine
por: Glass, Daniel J, et al.
Publicado: (2003)

Exposure of Fexofenadine, but Not Pseudoephedrine, Is Markedly Decreased by Green Tea Extract in Healthy Volunteers
por: Misaka, Shingen, et al.
Publicado: (2022)

Correction to: Insights into urticaria in pediatric and adult populations and its management with fexofenadine hydrochloride
por: Ansotegui, Ignacio J., et al.
Publicado: (2022)

Correction: Fexofenadine: review of safety, efficacy and unmet needs in children with allergic rhinitis
por: Meltzer, Eli O., et al.
Publicado: (2022)

Effectiveness of bilastine and fexofenadine among allergic Rhinitis patients in Ranchi, Jharkhand, India
por: Kumari, Abha, et al.
Publicado: (2022)

A Validated Stability-Indicating RP-UPLC Method for Simultaneous Determination of Desloratadine and Sodium Benzoate in Oral Liquid Pharmaceutical Formulations
por: Kumar, Navneet, et al.
Publicado: (2012)

Basic and clinical immunology – 3023. Influence of fexofenadine hydrochloride on uteroglobin production from nasal epithelial cells in vitro and in vivo
por: Kanai, Kenichi, et al.
Publicado: (2013)

Improved Dissolution Rate and Intestinal Absorption of Fexofenadine Hydrochloride by the Preparation of Solid Dispersions: In Vitro and In Situ Evaluation
por: Eedara, Basanth Babu, et al.
Publicado: (2021)

Solid Form and Phase Transformation Properties of Fexofenadine Hydrochloride during Wet Granulation Process
por: Li, Suye, et al.
Publicado: (2021)

Development and Validation of a Stability-Indicating RP-UPLC Method for the Estimation of Impurities in Cinacalcet Hydrochloride API and its Formulation
por: Sunil Reddy, Pingili, et al.
Publicado: (2015)

Improvement of effect of water-in-oil microemulsion as an oral delivery system for fexofenadine: in vitro and in vivo studies
por: Gundogdu, E, et al.
Publicado: (2011)

Basic and clinical immunology – 3022. Inhibitory action of fexofenadine hydrochloride on mast cell activation in vitro
por: Suzuki, Miyuki, et al.
Publicado: (2013)

Double blind randomized crossover trial of PF-03654764+fexofenadine in the environmental exposure unit (EEU)
por: North, Michelle L, et al.
Publicado: (2014)

Antihistamine effects and safety of fexofenadine: a systematic review and Meta-analysis of randomized controlled trials
por: Huang, Cheng-zhi, et al.
Publicado: (2019)

Application of green first derivative synchronous spectrofluorometric method for quantitative analysis of fexofenadine hydrochloride and pseudoephedrine hydrochloride in pharmaceutical preparation and spiked human plasma
por: Ramzy, Sherif, et al.
Publicado: (2022)

Does Ethnic Variability Exist in the Systemic Exposures of OATP1A2 Substrates–Fexofenadine in Taiwanese?
por: Chen, Y. A., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_sq147qmhsp3krchhls9uqn3lm5