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Wnt3a-stimulated LRP6 phosphorylation is dependent upon arginine methylation of G3BP2
Wnt signaling is initiated upon binding of Wnt proteins to Frizzled proteins and their co-receptors LRP5 and 6. The signal is then propagated to several downstream effectors, mediated by the phosphoprotein scaffold, dishevelled. We report a novel role for arginine methylation in regulating Wnt3a-sti...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Company of Biologists
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383259/ https://www.ncbi.nlm.nih.gov/pubmed/22357953 http://dx.doi.org/10.1242/jcs.100933 |