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Wnt3a-stimulated LRP6 phosphorylation is dependent upon arginine methylation of G3BP2

Wnt signaling is initiated upon binding of Wnt proteins to Frizzled proteins and their co-receptors LRP5 and 6. The signal is then propagated to several downstream effectors, mediated by the phosphoprotein scaffold, dishevelled. We report a novel role for arginine methylation in regulating Wnt3a-sti...

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Detalles Bibliográficos
Autores principales: Bikkavilli, Rama Kamesh, Malbon, Craig C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Company of Biologists 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383259/
https://www.ncbi.nlm.nih.gov/pubmed/22357953
http://dx.doi.org/10.1242/jcs.100933

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