Detecting BRAF Mutations in Formalin-Fixed Melanoma: Experiences with Two State-of-the-Art Techniques

BACKGROUND: Melanoma is characterized by a high frequency of BRAF mutations. It is unknown if the BRAF mutation status has any predictive value for therapeutic approaches such as angiogenesis inhibition. PATIENTS AND METHODS: We used 2 methods to analyze the BRAF mutation status in 52 of 62 melanoma...

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Detalles Bibliográficos
Autores principales: Schoenewolf, Nicola L., Dummer, Reinhard, Mihic-Probst, Daniela, Moch, Holger, Simcock, Mathew, Ochsenbein, Adrian, Gillessen, Silke, Schraml, Peter, von Moos, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Published online: June, 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383294/
https://www.ncbi.nlm.nih.gov/pubmed/22740817
http://dx.doi.org/10.1159/000339300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383294/
https://www.ncbi.nlm.nih.gov/pubmed/22740817
http://dx.doi.org/10.1159/000339300

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