Hyperglycemia and Renal Mass Ablation Synergistically Augment Albuminuria in the Diabetic Subtotally Nephrectomized Rat: Implications for Modeling Diabetic Nephropathy

BACKGROUND/AIMSBACKGROUND/AIMS: While experimental models that emulate diabetic nephropathy are valuable tools for elucidating pathogenetic mechanisms and developing novel therapies, existing models imperfectly recapitulate human disease. In diabetes, hyperglycemia and hemodynamic forces act in conc...

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Detalles Bibliográficos
Autores principales: Chen, Li-Hao, Stead, Bailey, Advani, Suzanne L., Yaqoob, Noreen, Thai, Kerri, Kabir, M. Golam, Yuen, Darren A., Connelly, Kim A., Gilbert, Richard E., Advani, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383305/
https://www.ncbi.nlm.nih.gov/pubmed/22739500
http://dx.doi.org/10.1159/000338272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383305/
https://www.ncbi.nlm.nih.gov/pubmed/22739500
http://dx.doi.org/10.1159/000338272

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